Radiodermatitis in older patients with head and neck cancer
Abstract
Objective: To analyze the incidence of radiodermatitis in older individuals with head and neck cancer undergoing radiotherapy. Method: Observational, prospective, quantitative study. The study included patients aged 60 years or older with head and neck cancer who underwent radiotherapy. Patients were monitored daily during radiotherapy sessions. Skin was assessed using the Acute Radiodermatitis Grading scale, and the occurrence of radiodermatitis and associated signs and symptoms in the irradiated area and skin hydration were recorded. Results: Thirty-three participants were monitored, who were submitted to an average of 33 radiotherapy sessions. Radiodermatitis occurred in 93.9% of participants, with an average dose of 34.7 Gy of ionizing radiation. Symptoms of heat, burning, itching, dry skin, and pain, present in 68% of participants, were reported most often in the fifth week of radiotherapy. Regarding skin hydration, most participants showed a marked imbalance, characterized by low moisture and oiliness. Conclusion: Most patients monitored displayed signs and symptoms of radiodermatitis during radiotherapy sessions. Nurses play a fundamental role in assessing, monitoring the skin, and providing health education on skin care for older patients during radiotherapy, aiming to prevent signs and symptoms of radiodermatitis.
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Nolen SC, Evans MA, Fischer A, Corrada MM, Kawas CH, Bota DA. Cancer-Incidence, prevalence and mortality in the oldest-old. A comprehensive review. Mech Ageing Dev. 2017;164:113-26. https://doi.org/10.1016/j.mad.2017.05.002
Brasil. Ministério da Saúde. Instituto Nacional de Câncer José Alencar Gomes da Silva. Coordenação de Prevenção e Vigilância. Estimativa 2022: incidência de câncer no Brasil. Rio de Janeiro: INCA; 2022.
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-24. https://doi.org/10.3322/caac.21492
Machtay M, Moughan J, Trotti A, Garden AS, Weber RS, Cooper JS, et al. Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis. J Clin Oncol. 2008;26(21):3582-9. https://doi.org/10.1200/JCO.2007.14.8841
Wang H, Mu X, He H, Zhang XD. Cancer radiosensitizers. Trends Pharmacol Sci. 2018;39(1):24-48. https://doi.org/10.1016/j.tips.2017.11.003
Gong L, Zhang Y, Liu C, Zhang M, Han S. Application of radiosensitizers in cancer radiotherapy. Int J Nanomedicine. 2021;16:1083-102. https://doi.org/10.2147/IJN.S290438
Bernardo AFC, Santos K, Silva DP. Pele: alterações anatômicas e fisiológicas do nascimento à maturidade. Rev Saúde Foco. 2019;1(11):1221-33.
Bontempo PSM, Ciol MA, Menêses AG, Simino GPR, Ferreira EB, Reis PED. Acute radiodermatitis in cancer patients: incidence and severity estimates. Rev Esc Enferm USP. 2021;55:e03676. https://doi.org/10.1590/S1980-220X2019021703676
Simman R, Bach K, Abbas F, Klomparens K, Brickman BJ. Management of radiation-induced tissue injuries: a review of current treatment strategies. Plast Reconstr Surg Glob Open. 2023;11(6):e5043. https://doi.org/10.1097/gox.0000000000005043
Xie Y, Wang Q, Hu T, Chen R, Wang J, Chang H, et al. Risk factors related to acute radiation dermatitis in breast cancer patients after radiotherapy: a systematic review and meta-analysis. Front Oncol. 2021;11:738851. https://doi.org/10.3389/fonc.2021.738851
Cruz FOAM, Ferreira EB, Vasques CI, Mata LRF, Reis PED. Validation of an educative manual for patients with head and neck cancer submitted to radiation therapy. Rev Lat Am Enfermagem. 2016;24:e2706. https://doi.org/10.1590%2F1518-8345.0949.2706
Cruz FOAM, Ferreira EB, Bontempo PSM, Vasques CI, Reis PED. Face validation of an educative manual for head and neck cancer patients submitted to radiotherapy. Biosci J. 2017;33(6):1688-95. https://doi.org/10.14393/BJ-v33n6a2017-34674
Reis PED, Ferreira EB, Bontempo PMS. Radiodermatites: prevenção e tratamento. In: Diretrizes oncológicas 2. São Paulo: Doctor Press Ed. Científica; 2019. p.683-92.
Westermann TVA, Viana VR, Berto Junior C, Silva CBD, Carvalho ELS, Pupe CG. Measurement of skin hydration with a portable device (SkinUp® Beatuty Device) and comparison with the Corneometer®. Skin Res Technol. 2020;26(4):571-6. https://doi.org/10.1111/srt.12833
Instituto Nacional do Câncer. Atlas on-line de mortalidade. Tabulador [Internet]. 2021 [cited on Jul 13, 2021]. Available at: https://mortalidade.inca.gov.br/MortalidadeWeb/pages/Modelo10/consultar.xhtml#panelResultado
Trindade JLR. Envelhecimento da pele: revisão narrativa da evolução histológica [dissertação]. Porto: Universidade Fernando Pessoa; 2022.
Paal K, Stranz B, Thurner EM, Langsenlehner U, Renner W, Brunner TB, et al. Comprehensive geriatric assessment predicts radiation-induced acute toxicity in prostate cancer patients. Strahlenther Onkol. 2024;200(3):208-18. https://doi.org/10.1007/s00066-023-02132-3
Chugh R, Bisht YS, Nautiyal V, Jindal R. Factors influencing the severity of acute radiation-induced skin and mucosal toxicity in head and neck cancer. Cureus. 2021;13(9):e18147. https://doi.org/10.7759/cureus.18147
Brustolin AM. Idosos sobreviventes ao câncer: vivências durante e após o tratamento oncológico [dissertação]. Chapecó: Universidade Comunitária da Região de Chapecó; 2015.
Ozturk HF, Ergiden C. Radiotherapy/chemoradiotherapy for geriatric head and neck cancer patients. ACH Med J. 2023;3:266-74. https://doi.org/10.5505/achmedj.2023.66375
Waskevicz L, Waskevicz C, Nascimento VAS. Câncer de cabeça e pescoço: diagnóstico e qualidade de vida. Rev Saúde. 2023;14(3):44-51. https://doi.org/10.21727/rs.v14i3.3661
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Copyright (c) 2025 Amanda Gomes de Menêses, Luana Alves de Oliveira, Elaine Barros Ferreira, Paula Elaine Diniz dos Reis, Fatima Helena do Espírito Santo

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