• Paula de Souza Silva Freitas Universidade Federal do Espírito Santo − Programa de Pós-graduação em Enfermagem – Vitória (ES), Brasil.
  • Lucas Dalvi Armond Rezende Universidade Federal do Espírito Santo − Centro de Ciências da Saúde − Departamento de Enfermagem – Vitória (ES), Brasil.
  • Kelly Eduarda de Jesus Silva Universidade Federal do Espírito Santo − Centro de Ciências da Saúde − Departamento de Enfermagem – Vitória (ES), Brasil.
  • Bruno Henrique Fiorin Federal University of Espírito Santo (UFES)
  • Ramon Araújo dos Santos Universidade Federal do Espírito Santo − Programa de Pós-graduação em Enfermagem – Vitória (ES), Brasil.
  • Aline Oliveira Ramalho Universidade de São Paulo − Escola de Enfermagem − Hospital Sírio Libanês – São Paulo (SP), Brasil.


Objectives: The aim was to identify the benefits of using Dialkyl Carbamoyl Chloride for the treatment of biofilms in wounds. Methods: This is an integrative literature review that aimed to answer the guiding question: “What are the benefits of using Dialkyl Carbamoyl Chloride in the healing of skin lesions?”. The article selection stages resulted in 13 articles included. Results: The selected articles were grouped into two groups, namely: prevention and treatment of infection in wounds and prevention of surgical site infection, with nine productions in the first group and four in the second. Studies have shown that Dialkyl Carbamoyl Chloride attenuates colonization symptoms, such as odor, pain complaints and oozing, in addition to aiding in the prophylactic management of wound biofilm. Evidence indicates that dressings with Dialkyl Carbamoyl Chloride have no adverse effects, making them viable and safe options for chronic, acute and, mainly, infected injuries. Conclusion: It was identified that Dialkyl Carbamoyl Chloride was able to promote beneficial actions in the treatment of wounds, especially those of greater complexity. The proper choice of dressings and coverings can contribute to the rational use of existing technologies and antimicrobials, culminating in cost reduction and promotion of quality of life for individuals with chronic wounds.


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How to Cite

de Souza Silva Freitas P, Rezende LDA, Eduarda de Jesus Silva K, Fiorin BH, Araújo dos Santos R, Ramalho AO. USE OF DIALKYL CARBAMOYL CHLORIDE IN THE PREVENTION AND TREATMENT OF BIOFILM IN WOUNDS. ESTIMA [Internet]. 2021 Jul. 16 [cited 2024 Apr. 17];19. Available from:



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